Mammalian Genomics

Hardback  624 pp  ISBN 0851999107      £120.00

• Brings together a diverse range of genomic studies relevant to mammals, including humans
• Is written by leading international researchers working in different areas of mammalian genetics and genomics
• Presents both classic studies and the latest research findings in gene mapping and related topics

Readership: Researchers and academics in human and animal genetics, and animal breeding.

Contents

Part 1. Organization of the Mammalian Genome

Linkage mapping, C Moran and J W James, University of Sydney, Australia
Mapping genomes at the chromosome level, B P Chowdhary and T Raudsepp, Texas A&M University, USA
Mapping genomes at the molecular level, F Galibert, Universite de Rennes, France, and N E Cockett, Utah State Univeristy, USA
DNA sequence of the human and other mammalian genomes, D Vaiman, INSERM, France

Part 2. Expression of the Mammalian Genome
The transcriptome, A Verger and M Crossley, University of Sydney, Australia
The proteome, M B Datto and T A Haystead, Duke University, USA
The epigenome - epigenetic regulation of gene expression in mammalian species, E Whitelaw, University of Sydney, and D Garrick, John Radcliffe Hospital, Oxford, UK
Regulation of genome activity and genetic networks in mammals, V Van Buren, and M S H Ko, National Institute of Health, USA
Inducing alterations in the mammalian genome for investigating the function of genes, J L Guénet, Institut Pasteur, France

Part 3. Evolution of the Mammalian Genome
Mammalian genomes in context, M I Bellgard, Murdoch University, Australia, and T Gojobori, National Institute of Genetics, Japan
Elements and mechanisms of genome change, R J O€Neill, G C Ferreri and M J O€Neil, University of Connecticut, USA
DNA sequence evolution and phylogenetic footprinting, E T Dermitzakis, The Wellcome Trust Sanger Institute, Cambridge, UK, and A Reymond, University of Geneva Medical School, Switzerland
The evolution of the mammalian karyotype, F Pardo-Manuel de Villena, University of North Carolina at Chapel Hill, USA
Comparative gene mapping and chromosome painting in mammals and the reconstruction of the ancestral mammalian karyotype, O L Serov, Russian Academy of Sciences, Russia, B P Chowdhary, J E Womack, Texas A&M University, USA, and J A Marshall Graves, The Australian National University, Australia

Part 4. Genome Analysis and Bioinformatics
Bioinformatics: from computational analysis through to integrated systems, M I Bellgard
Genetic databases, V Brusic and J L Y Koh, Institute for Infocomm Research, Singapore
Gene predictions and annotations, R Guidó, Universitat Pompeu Fabra, Spain, and M Q Zhang, Cold Spring Harbor Laboratory, USA

Part 5. The Fruits of Mammalian Genomics
Genomic research and progress in understanding inherited disorders in humans and other mammals, D R Sargan, University of Cambridge, UK, and A I Agoulnik, Baylor College of Medicine, Houston, USA
Pharmacogenomics, W W Weber and J M Rae, University of Michigan School of Medicine, USA
Genome scanning for quantitative trait loci, B J Hayes, Agricultural University of Norway, Norway, B P Kinghorn, and A Ruvinsky, University of New England, Australia
Mammalian population genetics and genomics, L Chikhi, Université Paul Sabatier, France, and M Bruford, Cardiff University, UK